A text-mining approach to study the real-world effectiveness and potentially fatal immune-related adverse events of PD-1 and PD-L1 inhibitors in older patients with stage III/IV non-small cell lung cancer

A text-mining approach to study the real-world effectiveness and potentially fatal immune-related adverse events of PD-1 and PD-L1 inhibitors in older patients with stage III/IV non-small cell lung cancer

Abstract Background This study was designed to investigate the impact of age on the effectiveness and immune-related adverse events (irAEs) of programmed death-(ligand)1 [PD-(L)1] inhibitors in patients with non-small cell lung cancer (NSCLC) using a novel text-mining technique. Methods This retrosp...

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Bibliographic Details
Main Authors: Hanieh Abedian Kalkhoran, Juliëtte Zwaveling, Bert N. Storm, Sylvia A. van Laar, Johanneke EA Portielje, Henk Codrington, Dieuwke Luijten, Pepijn Brocken, Egbert F. Smit, Loes E. Visser
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Cancer
Subjects:
Non-small cell lung cancer (NSCLC)
Immune checkpoint inhibitor (ICI)
Anti-PD-(L)1 therapy
Real-world
Elderly
Online Access:https://doi.org/10.1186/s12885-023-10701-z

Internet

https://doi.org/10.1186/s12885-023-10701-z

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