Clinical impact of IDH1 mutations and MGMT methylation in adult glioblastoma

Clinical impact of IDH1 mutations and MGMT methylation in adult glioblastoma

Abstract Background Impact of Isocitrate dehydrogenase1 (IDH1) and O6-methylguanine-DNA methyltransferase (MGMT) in glioblastoma (GBM) have been of great interest due to their implications in prediction of prognosis of several types of cancer. It was aimed to investigate the clinical role of IDH1 mu...

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Bibliographic Details
Main Authors: Magda Sayed Mahmoud, Mohamed K. Khalifa, Amira M. Nageeb, Lobna R. Ezz El-Arab, Manal El-Mahdy, Amal Ramadan, Maha Hashim, Noha M. Bakr, Menha Swellam
Format: Article
Language:English
Published: SpringerOpen 2024-03-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Glioblastoma
IDH1
MGMT
Temozolomide
Prognosis
Online Access:https://doi.org/10.1186/s43042-024-00516-3

Internet

https://doi.org/10.1186/s43042-024-00516-3

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