Identification of 3' UTR motifs required for mRNA localization to myelin sheaths in vivo.

Myelin is a specialized membrane produced by oligodendrocytes that insulates and supports axons. Oligodendrocytes extend numerous cellular processes, as projections of the plasma membrane, and simultaneously wrap multiple layers of myelin membrane around target axons. Notably, myelin sheaths origina...

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Bibliographic Details
Main Authors: Katie M Yergert, Caleb A Doll, Rebecca O'Rouke, Jacob H Hines, Bruce Appel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001053