NF-κB signaling regulates myelination in the CNS

Besides myelination of neuronal axons by oligodendrocytes to facilitate propagation of action potentials, oligodendrocytes also support axon survival and function. A key transcription factor involved in these processes is nuclear factor-κB (NF-κB), a hetero- or homodimer of the Rel family of protein...

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Bibliographic Details
Main Authors: Thomas eBlank, Marco ePrinz
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00047/full