Model‐based assessment of neutrophil‐mediated phagocytosis and digestion of bacteria across in vitro and in vivo studies

Abstract Neutrophil granulocytes are key components of the host response against pathogens, and severe neutropenia, with neutrophil counts below 0.5 × 106 cells/mL, renders patients increasingly vulnerable to infections. Published in vitro (n = 7) and in vivo (n = 5) studies with time‐course informa...

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Bibliographic Details
Main Authors: Anders Thorsted, Anh Duc Pham, Lena E. Friberg, Elisabet I. Nielsen
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.13046