Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery

Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery

Mitochondrial cristae organization and ER-mitochondria contact sites are critical structures for cellular function. Here, the authors use super-resolution microscopy to show that Miro GTPases form clusters required for normal ER-mitochondria contact sites formation and to link cristae organization t...

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Bibliographic Details
Main Authors: Souvik Modi, Guillermo López-Doménech, Elise F. Halff, Christian Covill-Cooke, Davor Ivankovic, Daniela Melandri, I. Lorena Arancibia-Cárcamo, Jemima J. Burden, Alan R. Lowe, Josef T. Kittler
Format: Article
Language:English
Published: Nature Portfolio 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12382-4

Internet

https://doi.org/10.1038/s41467-019-12382-4

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