Succinate dehydrogenase inversely regulates red cell distribution width and healthy life span in chronically hypoxic mice

Succinate dehydrogenase inversely regulates red cell distribution width and healthy life span in chronically hypoxic mice

Increased red cell distribution width (RDW), which measures erythrocyte mean corpuscular volume (MCV) variability (anisocytosis), has been linked to early mortality in many diseases and in older adults through unknown mechanisms. Hypoxic stress has been proposed as a potential mechanism. However, ex...

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Bibliographic Details
Main Authors: Bora E. Baysal, Abdulrahman A. Alahmari, Tori C. Rodrick, Debra Tabaczynski, Leslie Curtin, Mukund Seshadri, Drew R. Jones, Sandra Sexton
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-09-01
Series:JCI Insight
Subjects:
Hematology
Pulmonology
Online Access:https://doi.org/10.1172/jci.insight.158737

Internet

https://doi.org/10.1172/jci.insight.158737

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