GSK3A is redundant with GSK3B in modulating drug resistance and chemotherapy-induced necroptosis.

GSK3A is redundant with GSK3B in modulating drug resistance and chemotherapy-induced necroptosis.

Glycogen Synthase Kinase-3 alpha (GSK3A) and beta (GSK3B) isoforms are encoded by distinct genes, are 98% identical within their kinase domain and perform similar functions in several settings; however, they are not completely redundant and, depending on the cell type and differentiative status, the...

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Bibliographic Details
Main Authors: Emanuela Grassilli, Leonarda Ianzano, Sara Bonomo, Carola Missaglia, Maria Grazia Cerrito, Roberto Giovannoni, Laura Masiero, Marialuisa Lavitrano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4077702?pdf=render

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http://europepmc.org/articles/PMC4077702?pdf=render

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