Leveraging genetic overlap between irritability and psychiatric disorders to identify genetic variants of major psychiatric disorders

Abstract Irritability is a heritable core mental trait associated with several psychiatric illnesses. However, the genomic basis of irritability is unclear. Therefore, this study aimed to 1) identify the genetic variants associated with irritability and investigate the associated biological pathways...

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Bibliographic Details
Main Authors: Kyeongmin Jung, Joohyun Yoon, Yeeun Ahn, Soyeon Kim, Injeong Shim, Hyunwoong Ko, Sang-Hyuk Jung, Jaeyoung Kim, Hyejin Kim, Dong June Lee, Soojin Cha, Hyewon Lee, Beomsu Kim, Min Young Cho, Hyunbin Cho, Dan Say Kim, Jinho Kim, Woong-Yang Park, Tae Hwan Park, Kevin S. O`Connell, Ole A. Andreassen, Woojae Myung, Hong-Hee Won
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01005-0