Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet*

Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet*

The methionine choline-deficient (MCD) diet results in liver injury similar to human nonalcoholic steatohepatitis (NASH). The aims of this study were to define mechanisms of MCD-induced steatosis in insulin-resistant db/db and insulin-sensitive db/m mice. MCD-fed db/db mice developed more hepatic st...

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Bibliographic Details
Main Authors: Mary E. Rinella, Marc S. Elias, Robin R. Smolak, Tao Fu, Jayme Borensztajn, Richard M. Green
Format: Article
Language:English
Published: Elsevier 2008-05-01
Series:Journal of Lipid Research
Subjects:
nonalcoholic steatohepatitis
db/db mouse
lipid metabolism
visceral fat
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520425945

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http://www.sciencedirect.com/science/article/pii/S0022227520425945

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