CD36 – a plausible modifier of disease phenotype in familial adenomatous polyposis

CD36 – a plausible modifier of disease phenotype in familial adenomatous polyposis

Abstract Background Familial adenomatous polyposis (FAP) is a well characterised genetic predisposition to early onset colorectal cancer (CRC) that is characterised by polyposis of the colon and rectum. Animal models have consistently suggested the role of modifier genes in determining disease pheno...

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Bibliographic Details
Main Authors: Merran Holmes, Toni Connor, Christopher Oldmeadow, Peter G. Pockney, Rodney J. Scott, Bente A. Talseth-Palmer
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
FAP
Disease phenotype
Polyposis
Modifier gene
CD36
Online Access:http://link.springer.com/article/10.1186/s13053-018-0096-y

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http://link.springer.com/article/10.1186/s13053-018-0096-y

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