The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment

The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment

First thought to orchestrate exclusively leukocyte trafficking, chemokines are now acknowledged for their multiple roles in the regulation of cell proliferation, differentiation, and survival. Dysregulation of their normal functions contributes to various pathologies, including inflammatory diseases...

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Bibliographic Details
Main Authors: Nathan Reynders, Dayana Abboud, Alessandra Baragli, Muhammad Zaeem Noman, Bernard Rogister, Simone P. Niclou, Nikolaus Heveker, Bassam Janji, Julien Hanson, Martyna Szpakowska, Andy Chevigné
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
chemokine receptor
CXCR3
CXCL11
CXCL10
CXCL9
CXCL4
tumor microenvironment
GPCR
ACKR3/CXCR7
Online Access:https://www.mdpi.com/2073-4409/8/6/613

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https://www.mdpi.com/2073-4409/8/6/613

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