O-GlcNAcylation is essential for therapeutic mitochondrial transplantation

Abstract Background Transplantation of mitochondria is increasingly explored as a novel therapy in central nervous system (CNS) injury and disease. However, there are limitations in safety and efficacy because mitochondria are vulnerable in extracellular environments and damaged mitochondria can ind...

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Bibliographic Details
Main Authors: Ji Hyun Park, Masayoshi Tanaka, Takafumi Nakano, Ester Licastro, Yoshihiko Nakamura, Wenlu Li, Elga Esposito, Emiri T. Mandeville, Sherry Hsiang-Yi Chou, MingMing Ning, Eng H. Lo, Kazuhide Hayakawa
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-023-00402-w