Tensor Decomposition-Based Unsupervised Feature Extraction Can Identify the Universal Nature of Sequence-Nonspecific Off-Target Regulation of mRNA Mediated by MicroRNA Transfection
MicroRNA (miRNA) transfection is known to degrade target mRNAs and to decrease mRNA expression. In contrast to the notion that most of the gene expression alterations caused by miRNA transfection involve downregulation, they often involve both up- and downregulation; this phenomenon is thought to be...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-06-01
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| Series: | Cells |
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| Online Access: | http://www.mdpi.com/2073-4409/7/6/54 |