Kurarinone Inhibits HCoV-OC43 Infection by Impairing the Virus-Induced Autophagic Flux in MRC-5 Human Lung Cells

Kurarinone is a prenylated flavonone isolated from the roots of <i>Sophora flavescens</i>. Among its known functions, kurarinone has both anti-apoptotic and anti-inflammatory properties. Coronaviruses (CoVs), including HCoV-OC43, SARS-CoV, MERS-CoV, and SARS-CoV-2, are the causative agen...

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Bibliographic Details
Main Authors: Jung Sun Min, Dong Eon Kim, Young-Hee Jin, Sunoh Kwon
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/9/7/2230