Neuroprotective Effects of Activated Protein C Involve the PARP/AIF Pathway against Oxygen-Glucose Deprivation in SH-SY5Y Cells

Protein C, a member of the zymogen family of serine proteases in plasma, is one of the several vitamin K dependent glycoproteins known to induce anti-apoptotic activity. However, the target molecule involved in the mechanism needs to be investigated. We sought to investigate the pathways involved in...

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Bibliographic Details
Main Authors: Mukesh Kumar Sriwastva, Remesh Kunjunni, Mutahar Andrabi, Kameshwar Prasad, Renu Saxena, Vivekanandhan Subbiah
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/10/12/959