Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains.

Viral spillover from animal reservoirs can trigger public health crises and cripple the world economy. Knowing which viruses are primed for zoonotic transmission can focus surveillance efforts and mitigation strategies for future pandemics. Successful engagement of receptor protein orthologs is nece...

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Bibliographic Details
Main Authors: Sarah M Roelle, Nidhi Shukla, Anh T Pham, Anna M Bruchez, Kenneth A Matreyek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001738