Prediction of individual treatment allocation between electroconvulsive therapy or ketamine using the Personalized Advantage Index

Abstract Electroconvulsive therapy (ECT) and ketamine are effective treatments for depression; however, evidence-based guidelines are needed to inform individual treatment selection. We adapted the Personalized Advantage Index (PAI) using machine learning to predict optimal treatment assignment to E...

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Bibliographic Details
Main Authors: Benjamin S. C. Wade, Ryan Pindale, James Luccarelli, Shuang Li, Robert C. Meisner, Stephen J. Seiner, Joan A. Camprodon, Michael E. Henry
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-025-01523-3