Blockade of Melatonin Receptors Abolishes Its Antiarrhythmic Effect and Slows Ventricular Conduction in Rat Hearts

Blockade of Melatonin Receptors Abolishes Its Antiarrhythmic Effect and Slows Ventricular Conduction in Rat Hearts

Melatonin has been reported to cause myocardial electrophysiological changes and prevent ventricular tachycardia or fibrillation (VT/VF) in ischemia and reperfusion. We sought to identify electrophysiological targets responsible for the melatonin antiarrhythmic action and to explore whether melatoni...

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Bibliographic Details
Main Authors: Aleksandra V. Durkina, Barbara Szeiffova Bacova, Olesya G. Bernikova, Mikhail A. Gonotkov, Ksenia A. Sedova, Julie Cuprova, Marina A. Vaykshnorayte, Emiliano R. Diez, Natalia J. Prado, Jan E. Azarov
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
rat heart
post-ischemic arrhythmias
melatonin
conduction velocity
potassium current
sodium current
Online Access:https://www.mdpi.com/1422-0067/24/15/11931

Internet

https://www.mdpi.com/1422-0067/24/15/11931

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