Deep phenotypic profiling of neuroactive drugs in larval zebrafish
Abstract Behavioral larval zebrafish screens leverage a high-throughput small molecule discovery format to find neuroactive molecules relevant to mammalian physiology. We screen a library of 650 central nervous system active compounds in high replicate to train deep metric learning models on zebrafi...
Huvudupphovsmän: | , , , , , , , |
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Materialtyp: | Artikel |
Språk: | English |
Publicerad: |
Nature Portfolio
2024-11-01
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Serie: | Nature Communications |
Länkar: | https://doi.org/10.1038/s41467-024-54375-y |