Characterization of spontaneous bone marrow recovery after sublethal total body irradiation: importance of the osteoblastic/adipocytic balance.

Many studies have already examined the hematopoietic recovery after irradiation but paid with very little attention to the bone marrow microenvironment. Nonetheless previous studies in a murine model of reversible radio-induced bone marrow aplasia have shown a significant increase in alkaline phosph...

Full description

Bibliographic Details
Main Authors: Géraldine Poncin, Aurore Beaulieu, Chantal Humblet, Albert Thiry, Kimimitsu Oda, Jacques Boniver, Marie-Paule Defresne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281884?pdf=render