Biallelic Variants in <i>ENDOG</i> Associated with Mitochondrial Myopathy and Multiple mtDNA Deletions

Biallelic Variants in <i>ENDOG</i> Associated with Mitochondrial Myopathy and Multiple mtDNA Deletions

Endonuclease G (ENDOG) is a nuclear-encoded mitochondrial-localized nuclease. Although its precise biological function remains unclear, its proximity to mitochondrial DNA (mtDNA) makes it an excellent candidate to participate in mtDNA replication, metabolism and maintenance. Indeed, several roles fo...

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Bibliographic Details
Main Authors: Alessia Nasca, Andrea Legati, Megi Meneri, Melisa Emel Ermert, Chiara Frascarelli, Nadia Zanetti, Manuela Garbellini, Giacomo Pietro Comi, Alessia Catania, Costanza Lamperti, Dario Ronchi, Daniele Ghezzi
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
endonuclease G
ENDOG
mitochondrial DNA
mitochondrial myopathy
multiple mtDNA deletions
Online Access:https://www.mdpi.com/2073-4409/11/6/974

Internet

https://www.mdpi.com/2073-4409/11/6/974

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