Design, synthesis and biological evaluation of spiroisoquinoline-pyrimidine derivatives as anticancer agents against MCF-7 cancer cell lines

Quinoline derived scaffolds have long been reported for their promising biological responses such as anti-Alzheimer, antituberculosis, antioxidants, anti-inflammatory etc. Pyrimidine, a versatile pharmacophore, has also been employed for developing a variety of bioactive molecules. Therefore, we env...

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Bibliographic Details
Main Authors: Shruti Gupta, Gaurav Bartwal, Ashima Singh, Jyoti Tanwar, J.M. Khurana
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715622001059