Enhancing Tamoxifen Therapy with α-Mangostin: Synergistic Antiproliferative Effects on Breast Cancer Cells and Potential Reduced Endometrial Impact

Enhancing Tamoxifen Therapy with α-Mangostin: Synergistic Antiproliferative Effects on Breast Cancer Cells and Potential Reduced Endometrial Impact

Breast cancer is the most prevalent neoplasia among women worldwide. For the estrogen receptor-positive (ER+) phenotype, tamoxifen is the standard hormonal therapy; however, it carries the risk of promoting endometrial carcinoma. Hence, we aimed to evaluate the antiproliferative effect of the phytoc...

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Bibliographic Details
Main Authors: Rafael Vargas-Castro, Rocío García-Becerra, Lorenza Díaz, Euclides Avila, David Ordaz-Rosado, Samantha V. Bernadez-Vallejo, Saúl Cano-Colín, Javier Camacho, Fernando Larrea, Janice García-Quiroz
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceuticals
Subjects:
α-mangostin
breast cancer
tamoxifen
combination index
synergism
endometrium cells
Online Access:https://www.mdpi.com/1424-8247/16/11/1576

Internet

https://www.mdpi.com/1424-8247/16/11/1576

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