Bi-alignments with affine gaps costs

Abstract Background Commonly, sequence and structure elements are assumed to evolve congruently, such that homologous sequence positions correspond to homologous structural features. Assuming congruent evolution, alignments based on sequence and structure similarity can therefore optimize both simil...

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Bibliographic Details
Main Authors: Peter F. Stadler, Sebastian Will
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Algorithms for Molecular Biology
Subjects:
Online Access:https://doi.org/10.1186/s13015-022-00219-7