Successful naltrexone-bupropion treatment after several treatment failures in a patient with severe monogenic obesity

Successful naltrexone-bupropion treatment after several treatment failures in a patient with severe monogenic obesity

Summary: We describe the therapeutic journey of a 33-year-old patient with early-onset obesity (BMI 56.7 kg/m2) and hyperphagia due to a likely pathogenic heterozygous melanocortin-4 receptor (MC4R) gene variant.She was unsuccessfully treated with several intensive lifestyle interventions, gastric b...

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Bibliographic Details
Main Authors: Mila S. Welling, Mostafa Mohseni, Eline S. van der Valk, Johanna M. van Hagen, Jan Steven Burgerhart, Mieke M. van Haelst, Elisabeth F.C. van Rossum
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:iScience
Subjects:
Biological sciences
Physiology
Human Physiology
Human metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223002766

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http://www.sciencedirect.com/science/article/pii/S2589004223002766

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