Changes in gut viral and bacterial species correlate with altered 1,2-diacylglyceride levels and structure in the prefrontal cortex in a depression-like non-human primate model

Abstract Major depressive disorder (MDD) is a debilitating mental disease, but its underlying molecular mechanisms remain obscure. Our previously established model of naturally occurring depression-like (DL) behaviors in Macaca fascicularis, which is characterized by microbiota-gut–brain (MGB) axis...

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Bibliographic Details
Main Authors: Jing Wu, Tingjia Chai, Hanping Zhang, Yu Huang, Seth W. Perry, Yifan Li, Jiajia Duan, Xunmin Tan, Xi Hu, Yiyun Liu, Juncai Pu, Haiyang Wang, Jinlin Song, Xin Jin, Ping Ji, Peng Zheng, Peng Xie
Format: Article
Language:English
Published: Nature Publishing Group 2022-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-01836-x