Effect of melatonin in patients with low anterior resection syndrome (MELLARS): a study protocol for a randomised, placebo-controlled, crossover trial
Introduction After rectal cancer surgery, a majority of patients suffer from sequelae known as low anterior resection syndrome (LARS). It is a collection of symptoms consisting of flatus and/or stool incontinence, evacuation frequency, re-evacuation and urgency. The circadian hormone, melatonin, has...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2023-09-01
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Series: | BMJ Open |
Online Access: | https://bmjopen.bmj.com/content/13/9/e067763.full |