Wnt Signaling Drives Prostate Cancer Bone Metastatic Tropism and Invasion

Wnt signaling has been implicated as a driver of prostate cancer-related osteoblast differentiation, and previous studies have linked modifications in Wnt function with the induction of tumor metastasis. A unique aspect of prostate cancer bone metastases in mouse models is their relative predilectio...

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Bibliographic Details
Main Authors: Yugang Wang, Udit Singhal, Yuanyuan Qiao, Tadas Kasputis, Jae-Seung Chung, Huiru Zhao, Farah Chammaa, Jacob A. Belardo, Therese M. Roth, Hao Zhang, Alexander B. Zaslavsky, Ganesh S. Palapattu, Kenneth J. Pienta, Arul M. Chinnaiyan, Russell S. Taichman, Frank C. Cackowski, Todd M. Morgan
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523319306291