Saturation Transfer Difference NMR and Molecular Docking Interaction Study of Aralkyl-Thiodigalactosides as Potential Inhibitors of the Human-Galectin-3 Protein

Saturation Transfer Difference NMR and Molecular Docking Interaction Study of Aralkyl-Thiodigalactosides as Potential Inhibitors of the Human-Galectin-3 Protein

Human Galectin-3 (<i>h</i>Gal-3) is a protein that selectively binds to β-galactosides and holds diverse roles in both normal and pathological circumstances. Therefore, targeting <i>h</i>Gal-3 has become a vibrant area of research in the pharmaceutical chemistry. As a step to...

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Bibliographic Details
Main Authors: Fanni Hőgye, László Bence Farkas, Álex Kálmán Balogh, László Szilágyi, Samar Alnukari, István Bajza, Anikó Borbás, Krisztina Fehér, Tünde Zita Illyés, István Timári
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
lectin
galectin-3
thiodigalactosides
NMR spectroscopy
STD NMR
molecular docking
Online Access:https://www.mdpi.com/1422-0067/25/3/1742

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https://www.mdpi.com/1422-0067/25/3/1742

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