CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis

Human immunodeficiency virus (HIV) infection is principally a mucosal disease and the gastrointestinal (GI) tract is the major site of HIV replication. Loss of CD4+ T cells and systemic immune hyperactivation are the hallmarks of HIV infection. The end of acute infection is associated with the emerg...

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Bibliographic Details
Main Authors: Angelita Rebollo, Karim Dorgham, Michèle Février
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/3/5/586/