Specific knockout of p85α in brown adipose tissue induces resistance to high-fat diet–induced obesity and its metabolic complications in male mice

Objective: An increase in mass and/or brown adipose tissue (BAT) functionality leads to an increase in energy expenditure, which may be beneficial for the prevention and treatment of obesity. Moreover, distinct class I PI3K isoforms can participate in metabolic control as well as in systemic dysfunc...

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Bibliographic Details
Main Authors: Almudena Gomez-Hernandez, Andrea R. Lopez-Pastor, Carlota Rubio-Longas, Patrik Majewski, Nuria Beneit, Vanesa Viana-Huete, Gema García-Gómez, Silvia Fernandez, Marta Letizia Hribal, Giorgio Sesti, Oscar Escribano, Manuel Benito
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819309366