Qiang-Xin 1 Formula Prevents Sepsis-Induced Apoptosis in Murine Cardiomyocytes by Suppressing Endoplasmic Reticulum- and Mitochondria-Associated Pathways

Qiang-Xin 1 Formula Prevents Sepsis-Induced Apoptosis in Murine Cardiomyocytes by Suppressing Endoplasmic Reticulum- and Mitochondria-Associated Pathways

Sepsis is reported to be an unusual systemic reaction to infection, accompanied by multiple-organ failure. Sepsis-induced cardiomyopathy (SIC), defined as damages and dysfunction of the heart, is essential in the pathogenesis of sepsis. Traditional Chinese formula, which has long been used to improv...

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Bibliographic Details
Main Authors: Xiaolong Xu, Qingquan Liu, Shasha He, Jingxia Zhao, Ning Wang, Xuyang Han, Yuhong Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Pharmacology
Subjects:
apoptosis
ER stress
mitochondria
murine
sepsis
traditional Chinese medicine
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00818/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00818/full

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