A comparison of classical and H-type bovine spongiform encephalopathy associated with E211K prion protein polymorphism in wild type and EK211 cattle following intracranial inoculation

A comparison of classical and H-type bovine spongiform encephalopathy associated with E211K prion protein polymorphism in wild type and EK211 cattle following intracranial inoculation

In 2006, a case of H-type bovine spongiform encephalopathy (BSE-H) was diagnosed in a cow that was associated with a heritable polymorphism in the bovine prion protein gene (PRNP) resulting in a lysine for glutamine amino acid substitution at codon 211 (called E211K) of the prion protein. Although t...

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Bibliographic Details
Main Authors: Jo Moore, M. Heather West Greenlee, Jodi D. Smith, Catherine E. Vrentas, Eric M Nicholson, Justin J Greenlee
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Veterinary Science
Subjects:
Brain Diseases
Cattle
prion protein
Bovine spongiform encephalopathy
E211K
transmissible spongiform encephalopathy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fvets.2016.00078/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fvets.2016.00078/full

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