The <i>TP53</i> Codon 72 Arginine Polymorphism Is Found with Increased <i>TP53</i> Somatic Mutations in HPV(−) and in an Increased Percentage among HPV(+) Norwegian HNSCC Patients

The <i>TP53</i> Codon 72 Arginine Polymorphism Is Found with Increased <i>TP53</i> Somatic Mutations in HPV(−) and in an Increased Percentage among HPV(+) Norwegian HNSCC Patients

Background: Somatic <i>TP53</i> mutations are frequent in head and neck squamous cell carcinoma (HNSCC) and are important pathogenic factors. Objective: To study <i>TP53</i> mutations relative to the presence of human papillomavirus (HPV) in tumors in HNSCC patients. Methods:...

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Bibliographic Details
Main Authors: Svein Erik Moe, Fredrik A. Erland, Siren Fromreide, Stein Lybak, Marianne Brydoy, Harsh N. Dongre, Sophia M. Dhayalan, Daniela-Elena Costea, Olav K. Vintermyr, Hans Jørgen Aarstad
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomedicines
Subjects:
head and neck cancer
<i>TP53</i>
somatic mutation
singe-nucleotide polymorphism
HPV
Online Access:https://www.mdpi.com/2227-9059/11/7/1838

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https://www.mdpi.com/2227-9059/11/7/1838

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