C3: connect separate connected components to form a succinct disease module

C3: connect separate connected components to form a succinct disease module

Abstract Background Precise disease module is conducive to understanding the molecular mechanism of disease causation and identifying drug targets. However, due to the fragmentization of disease module in incomplete human interactome, how to determine connectivity pattern and detect a complete neigh...

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Bibliographic Details
Main Authors: Bingbo Wang, Jie Hu, Yajun Wang, Chenxing Zhang, Yuanjun Zhou, Liang Yu, Xingli Guo, Lin Gao, Yunru Chen
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Bioinformatics
Subjects:
Disease module
Connectivity pattern
Biological network
Online Access:http://link.springer.com/article/10.1186/s12859-020-03769-y

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http://link.springer.com/article/10.1186/s12859-020-03769-y

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