Restored and Enhanced Memory T Cell Immunity in Rheumatoid Arthritis After TNFα Blocker Treatment

Restored and Enhanced Memory T Cell Immunity in Rheumatoid Arthritis After TNFα Blocker Treatment

TNFα inhibitors have shaped the landscape of rheumatoid arthritis (RA) therapy with high clinical efficiency. However, their impact on T cell recall responses is not well-elucidated. We aimed to analyze the immune profiles of memory T cells in RA patients undergoing TNFα inhibitor Golimumab (GM) tre...

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Bibliographic Details
Main Authors: Asma Khanniche, Ling Zhou, Bin Jiang, Jing Song, Yanhua Jin, Jian Yin, Shujun Wang, Ping Ji, Hao Shen, Ying Wang, Huji Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
memory T cells
antigen specific
TNFα inhibitor
immune regulation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00887/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00887/full

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