Association between genetic variants in TREM1, CXCL10, IL4, CXCL8 and TLR7 genes with the occurrence of congenital Zika syndrome and severe microcephaly

Abstract Congenital Zika syndrome (CZS) is a cluster of malformations induced by Zika virus (ZIKV) infection and the underline mechanisms involved in its occurrence are yet not fully understood. Along with epidemiological and environmental factors, the genetic host factors are suggested as important...

Full description

Bibliographic Details
Main Authors: Camilla Natália Oliveira Santos, Lucas Sousa Magalhães, Adriana Barbosa de Lima Fonseca, Ana Jovina Barreto Bispo, Roseane Lima Santos Porto, Juliana Cardoso Alves, Cliomar Alves dos Santos, Jaira Vanessa de Carvalho, Angela Maria da Silva, Mauro Martins Teixeira, Roque Pacheco de Almeida, Priscila Lima dos Santos, Amélia Ribeiro de Jesus
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30342-3