Effects of Stress Exposure to Pain Perception in Pre-Clinical Studies: Focus on the Nociceptin/Orphanin FQ–NOP Receptor System

Exposure to physical and psychological stress modulates pain transmission in a dual manner. Stress-induced analgesia (SIA) refers to the reduction in pain sensitivity that can occur in response to acute stress. On the contrary, chronic stress exposure may lead to a phenomenon named stress-induced hy...

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Bibliographic Details
Main Authors: Pietro Pola, Alessia Frezza, Elaine C. Gavioli, Girolamo Calò, Chiara Ruzza
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/14/9/936