Neopterin Counters Vascular Inflammation and Atherosclerosis

Neopterin Counters Vascular Inflammation and Atherosclerosis

BackgroundNeopterin, a metabolite of GTP, is produced by activated macrophages and is abundantly expressed within atherosclerotic lesions in human aorta and carotid and coronary arteries. We aimed to clarify the influence of neopterin on both vascular inflammation and atherosclerosis, as neither eff...

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Bibliographic Details
Main Authors: Remina Shirai, Kengo Sato, Tomoyuki Yamashita, Maho Yamaguchi, Taisuke Okano, Kaho Watanabe‐Kominato, Rena Watanabe, Taka‐aki Matsuyama, Hatsue Ishibashi‐Ueda, Shinji Koba, Youichi Kobayashi, Tsutomu Hirano, Takuya Watanabe
Format: Article
Language:English
Published: Wiley 2018-02-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atherosclerosis
endothelial cell
inflammation
macrophage
neopterin
smooth muscle cell
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.007359

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https://www.ahajournals.org/doi/10.1161/JAHA.117.007359

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