The Role of <i>SLC22A1</i> and Genomic Ancestry on Toxicity during Treatment in Children with Acute Lymphoblastic Leukemia of the Amazon Region

The Role of <i>SLC22A1</i> and Genomic Ancestry on Toxicity during Treatment in Children with Acute Lymphoblastic Leukemia of the Amazon Region

In Brazil, Acute lymphoid leukemia (ALL) is the leading cause of cancer deaths in children and adolescents. Treatment toxicity is one of the reasons for stopping chemotherapy. Amerindian genomic ancestry is an important factor for this event due to fluctuations in frequencies of genetic variants, as...

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Bibliographic Details
Main Authors: Sweny de S. M. Fernandes, Luciana P. C. Leitão, Amanda de N. Cohen-Paes, Laura P. A. Gellen, Lucas F. Pastana, Darlen C. de Carvalho, Antônio A. C. Modesto, Ana C. A. da Costa, Alayde V. Wanderley, Carlos H. V. de Lima, Esdras E. B. Pereira, Marianne R. Fernandes, Rommel M. R. Burbano, Paulo P. de Assumpção, Sidney E. B. dos Santos, Ney P. C. dos Santos
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Genes
Subjects:
acute lymphoid leukemia
severe toxicity
ancestry
<i>NUDT1</i>
SLC22A1
Online Access:https://www.mdpi.com/2073-4425/13/4/610

Internet

https://www.mdpi.com/2073-4425/13/4/610

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