Histopathological evaluation of Onchocerca volvulus nodules by microscopy and by digital image analysis for the study of macrofilaricidal drug efficacy

Histopathological evaluation of Onchocerca volvulus nodules by microscopy and by digital image analysis for the study of macrofilaricidal drug efficacy

BackgroundNovel drugs or drug combinations that kill or permanently sterilize adult Onchocerca volvulus worms would be very helpful for treatment and elimination of onchocerciasis. In absence of a reliable biomarker for viable adult worms, histopathological assessment of worms within onchocercal nod...

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Bibliographic Details
Main Authors: Kerstin Fischer, Bettina Dubben, Linda B. Debrah, Janina M. Kuehlwein, Arcangelo Ricchiuto, Alexander Y. Debrah, Achim Hoerauf, Gary J. Weil, Peter U. Fischer, Ute Klarmann-Schulz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Medicine
Subjects:
Onchocerca volvulus
histology
clinical trials
viability assessment
digital images
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1099926/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1099926/full

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