Appropriate Amounts and Activity of the Wilms’ Tumor Suppressor Gene, <i>wt1</i>, Are Required for Normal Pronephros Development of <i>Xenopus</i> Embryos
The Wilms’ tumor suppressor gene, <i>wt1</i>, encodes a zinc finger-containing transcription factor that binds to a GC-rich motif and regulates the transcription of target genes. <i>wt1</i> was first identified as a tumor suppressor gene in Wilms’ tumor, a pediatric kidney tu...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-10-01
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Series: | Journal of Developmental Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/2221-3759/10/4/46 |