Appropriate Amounts and Activity of the Wilms’ Tumor Suppressor Gene, <i>wt1</i>, Are Required for Normal Pronephros Development of <i>Xenopus</i> Embryos

The Wilms’ tumor suppressor gene, <i>wt1</i>, encodes a zinc finger-containing transcription factor that binds to a GC-rich motif and regulates the transcription of target genes. <i>wt1</i> was first identified as a tumor suppressor gene in Wilms’ tumor, a pediatric kidney tu...

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Bibliographic Details
Main Authors: Taisei Shiraki, Takuma Hayashi, Jotaro Ozue, Minoru Watanabe
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Journal of Developmental Biology
Subjects:
Online Access:https://www.mdpi.com/2221-3759/10/4/46