TNFR1 Absence Is Not Crucial for Different Types of Cell Reaction to TNF: A Study of the TNFR1-Knockout Cell Model

TNFR1 Absence Is Not Crucial for Different Types of Cell Reaction to TNF: A Study of the TNFR1-Knockout Cell Model

Background: One of the mechanisms regulating the biological activity of tumor necrosis factor (TNF) in cells is the co-expression of TNFR1/TNFR2 receptors. A model with a differential level of receptor expression is required to evaluate the contribution of these mechanisms. Aim: The development of a...

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Bibliographic Details
Main Authors: Alina A. Alshevskaya, Julia A. Lopatnikova, Julia V. Zhukova, Olga Y. Perik-Zavodskaia, Saleh Alrhmoun, Irina A. Obleukhova, Anna K. Matveeva, Darya A. Savenkova, Ilnaz R. Imatdinov, Dmitry V. Yudkin, Sergey V. Sennikov
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Epigenomes
Subjects:
TNF receptors
TNFR1
TNFR2
gene knockout
flow cytometry
receptor expression density
Online Access:https://www.mdpi.com/2075-4655/8/2/15

Internet

https://www.mdpi.com/2075-4655/8/2/15

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