Efficient TALEN-mediated mutagenesis on a highly conserved region of myostatin gene in mouse embryonic stem cells

Myostatin is a negative regulator of muscle growth. The naturally occurring mutations of myostatin gene (MSTN) are strongly associated with meat production traits in livestock. Thus far, many attempts have been made to knock- down/knock-out MSTN across numerous species. The main objective of this s...

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Bibliographic Details
Main Authors: A TAHERI-GHAHFAROKHI, M TAHMOORESPUR, H DEHGHANI, Y SHAMSHIRGARAN, H SUMER, J LIU, P J VERMA
Format: Article
Language:English
Published: Indian Council of Agricultural Research 2014-11-01
Series:Indian Journal of Animal Sciences
Subjects:
Online Access:https://epubs.icar.org.in/index.php/IJAnS/article/view/44725