Biomimetic doxorubicin/ginsenoside co-loading nanosystem for chemoimmunotherapy of acute myeloid leukemia

Abstract Background Acute myeloid leukemia (AML) showed limited clinical therapeutic efficiency with chemotherapy for its multi-distributed lesions and hard-to-kill leukemia cells deep in the bone marrow. Results Here, a biomimetic nanosystem (DR@PLip) based on platelet membrane (PM) coating and dox...

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Bibliographic Details
Main Authors: Mo Chen, Yingyu Qiao, Jie Cao, La Ta, Tianyuan Ci, Xue Ke
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-022-01491-w