Innate immunity of vascular smooth muscle cells contributes to two-wave inflammation in atherosclerosis, twin-peak inflammation in aortic aneurysms and trans-differentiation potential into 25 cell types

Innate immunity of vascular smooth muscle cells contributes to two-wave inflammation in atherosclerosis, twin-peak inflammation in aortic aneurysms and trans-differentiation potential into 25 cell types

IntroductionVascular smooth muscle cells (VSMCs) are the predominant cell type in the medial layer of the aorta, which plays a critical role in aortic diseases. Innate immunity is the main driving force for cardiovascular diseases. MethodsTo determine the roles of innate immunity in VSMC and aortic...

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Bibliographic Details
Main Authors: Qiaoxi Yang, Fatma Saaoud, Yifan Lu, Yujiang Pu, Keman Xu, Ying Shao, Xiaohua Jiang, Sheng Wu, Ling Yang, Ying Tian, Xiaolei Liu, Avrum Gillespie, Jin Jun Luo, Xinghua Mindy Shi, Huaqing Zhao, Laisel Martinez, Roberto Vazquez-Padron, Hong Wang, Xiaofeng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
VSMCs
vascular inflammation
trained immunity
nuclear stress
trans-differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1348238/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1348238/full

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