A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity.

Tigecycline is a broad-spectrum, first-in-class glycylcycline antibiotic currently used to treat complicated skin and intra-abdominal infections, as well as community-acquired pneumonia. In addition, we have demonstrated that tigecycline also has in vitro and in vivo activity against acute myeloid l...

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Bibliographic Details
Main Authors: Yulia Jitkova, Marcela Gronda, Rose Hurren, Xiaoming Wang, Carolyn A Goard, Bozhena Jhas, Aaron D Schimmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4037176?pdf=render