The T-cell repertoire of Spanish patients with COVID-19 as a strategy to link T-cell characteristics to the severity of the disease

The T-cell repertoire of Spanish patients with COVID-19 as a strategy to link T-cell characteristics to the severity of the disease

Abstract Background The architecture and dynamics of T cell populations are critical in orchestrating the immune response to SARS-CoV-2. In our study, we used T Cell Receptor sequencing (TCRseq) to investigate TCR repertoires in 173 post-infection COVID-19 patients. Methods The cohort included 98 mi...

Full description

Bibliographic Details
Main Authors: Fernando Marín-Benesiu, Lucia Chica-Redecillas, Verónica Arenas-Rodríguez, Esperanza de Santiago, Silvia Martínez-Diz, Ginesa López-Torres, Ana Isabel Cortés-Valverde, Catalina Romero-Cachinero, Carmen Entrala-Bernal, Francisco Javier Fernandez-Rosado, Luis Javier Martínez-González, Maria Jesus Alvarez-Cubero
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Human Genomics
Subjects:
T cells
SARS-Cov2
Immunoinformatics
COVID-19
Adaptative immunology
TCR repertoire
Online Access:https://doi.org/10.1186/s40246-024-00654-0

Internet

https://doi.org/10.1186/s40246-024-00654-0

Similar Items