Immune Response Gaps Linked to SARS-CoV-2 Infection: Cellular Exhaustion, Senescence, or Both?

Immune Response Gaps Linked to SARS-CoV-2 Infection: Cellular Exhaustion, Senescence, or Both?

The COVID-19 pandemic, promoted by the SARS-CoV-2 respiratory virus, has resulted in widespread global morbidity and mortality. The immune response against this pathogen has shown a thin line between protective effects and pathological reactions resulting from the massive release of cytokines and po...

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Bibliographic Details
Main Authors: Leonardo Vinicius Barbosa, Daniele Margarita Marani Prá, Seigo Nagashima, Marcos Roberto Curcio Pereira, Rebecca Benicio Stocco, Francys de Luca Fernandes da Silva, Milena Rueda Cruz, Djessyka Dallagassa, Thiago João Stupak, George Willian Xavier da Rosa Götz, Georgia Garofani Nasimoto, Luiz Augusto Fanhani Cracco, Isabela Busto Silva, Karen Fernandes de Moura, Marina de Castro Deus, Ana Paula Camargo Martins, Beatriz Akemi Kondo Van Spitzenbergen, Andréa Novais Moreno Amaral, Caroline Busatta Vaz de Paula, Cleber Machado-Souza, Lucia de Noronha
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
SARS-CoV-2
inflammation
pathogenesis
cellular exhaustion
senescence
CD8
Online Access:https://www.mdpi.com/1422-0067/23/22/13734

Internet

https://www.mdpi.com/1422-0067/23/22/13734

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